Queen Latifah works the runway with Jamie Foxx's sister at charity event

Jamie Foxx is quite the big brother.

Foxx was there once again to support his sister, DeOndra Dixon, at the annual gala-fashion show in Denver on Saturday to benefit the Global Down Syndrome Foundation.

The actor and recording artist got downright serious at arrivals about how his sis "lights up the room, just as big as any star."

Awe.

The siblings had lots of famous friends in the room to help celebrate. Among them: The evening's host Mario Lopez, actors John C. McGinley and Matt Dillon, retired NFL star Peyton Manning and Queen Latifah.

Latifah had the honor of escorting DeOndra down the runway during the fashion show portion of the evening.

Work it, ladies!