Global Down Syndrome Foundation | Research, Care, Education, Advocacy  

Linda Crnic Institute
for Down Syndrome

The Global Down Syndrome Foundation provides fundraising, education, awareness and government advocacy for the Linda Crnic Institute for Down Syndrome.

Established in 2008, the Linda Crnic Institute for Down Syndrome is the first academic home for Down syndrome research in the United States. The mission of the Crnic Institute is to significantly improve the lives of people with Down syndrome by eradicating the medical and cognitive ill effects associated with the condition.

Learn more about the Linda Crnic Institute.
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Keep up with research news, upcoming programs, events and educational conferences.

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Make sure your local Representatives are on the Congressional Down Syndrome Caucus.

  • The Salah Foundation Funds Global's Research Program
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    The Salah Foundation Funds Global's Research Program

  • Prestigious Symposia Focuses on Down Syndrome Research
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    Prestigious Symposia Focuses on Down Syndrome Research

  • Megan Bomgaars Living Life Without Limits
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    Megan Bomgaars Living Life Without Limits

  • DS Expert and Renowned Dietician Shares Three Important Takeaways
    Learn More

    DS Expert and Renowned Dietician Shares Three Important Takeaways

  • Be Beautiful Be Yourself Dance Classes at the Colorado Ballet
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    Be Beautiful Be Yourself Dance Classes at the Colorado Ballet

Blog

Marwan Sabbagh, M.D.$1 Million in Grants for Alzheimer Disease-Down Syndrome Research

POTENTIAL “ONE-DROP” BLOOD TEST AMONG NEW PROJECTS FUNDED BY ALZHEIMER’S ASSOCIATION AND GLOBAL DOWN SYNDROME FOUNDATION
 
 
 
 
 

Joan MedlenNutrition Expert Keynotes Global’s Education Series

Joan Medlen is a registered dietitian and DS expert who has published 2 popular books promoting healthy lifestyles for people who are differently-abled.

Global Down Syndrome Foundation
Fall 2015 Education Series
November 20-21, 2015
 
 
 
 
 

Hunt and Long
Longitudinal AD and DS Study at Crnic Institute
Help further research by participating in a study overseen by Dr. Huntington Potter and the Rocky Mountain Alzheimer’s Disease Center
 
 
 
 
 
 
Global Grant Funds Employment Initiative
Global celebrates Down Syndrome Awareness Month by announcing a new grant program that aims to increase jobs for self-advocates.
 
 
 
 
 
 

carlos-and-wifeCarlos González Goes to Bat for Global Down Syndrome Foundation
Rockies star player will strut his stuff on the runway to support Down syndrome research and medical care at Global’s Be Beautiful Be Yourself Fashion Show on Saturday, October 24, 2015
 
 
 
 
 
miss co dr ozMiss Colorado Supports Global and Appears on Dr. Oz
Miss Colorado will escort Global’s models with Down syndrome at the October 24 Be Beautiful Be Yourself Fashion Show. She responded to criticism and praise after advocating for nurses during her monologue for the talent portion of the Miss America pageant. Watch her TV appearances and viral monologue.
 
 
 
 

 

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Linda Crnic Institute for Down Syndrome
The Leader in scientific research benefiting people with Down syndrome

Meet the Crnic Institute Supergroup 2013 Grant Recipients

V. Balasubramaniam, M.D.
Sleep apnea and Down syndrome
Examine the effect of sleep apnea on vascular stem cells in people with Down syndrome
Christopher Link, Ph.D.
Genetic understanding of Down syndrome
Determine which genes have altered expression due to Trisomy 21
James DeGregori, Ph.D.
Leukemia and Down syndrome
Study increase in leukemia incidence and other problems with blood cell production, including reduced immunity
Karl Pfenninger, M.D.
Cognition and Down syndrome
Study causes of intellectual disability associated with Down syndrome, specifically the APP protein
Robin Dowell, Ph.D.
Genetic understanding of Down syndrome
Understand how Trisomy 21 affects the behavior of key proteins involved in regulating expression
Tamim H. Shaikh, Ph.D.
Autism and Down syndrome
Research genetic modifiers of autism spectrum disorders in patients with Down syndrome
Joaquin Espinosa, Ph.D.
Genetic understanding of Down syndrome
Identify genes whose function is essential in trisomic cells yet dispensable in cells with only two copies of chromosome 21
Richard Spritz, M.D.
Autoimmune disorders and Down syndrome
Analyze autoimmunity genetics in Down syndrome — thyroid disease, celiac disease, type 1 diabetes and rheumatoid arthritis
Fran Hickey, M.D.
Anesthesia and Down syndrome
Provide information to improve management of post-operative pain and sedation in children with Down syndrome
Ding Xue, Ph.D.
Alzheimer’s disease and Down syndrome
Study the roles of presenilin and ubiquilin in developing treatments for Alzheimer’s disease in patients with Down syndrome
Kevin Jones, Ph.D.
Gene regulation and Down syndrome
Test whether increasing the abundance of the BDNF protein can prevent Down syndrome pathology in a mouse model
Michael Yeager, Ph.D.
Autoimmune disorders and Down syndrome
Understand immune system disturbances in individuals with Down syndrome and drive development of newer therapies
Matthew Kennedy, Ph.D.
Alzheimer’s disease and Down syndrome
Investigate how increased beta-amyloid production causes synapse loss in hope of finding targets for future therapies
Rui Yi, Ph.D.
Genetic understanding of Down syndrome
Determine the effect of gene dosage imbalance on activity in trisomic embryonic stem cells

Meet the full Supergroup