Global Down Syndrome Foundation | Research, Care, Education, Advocacy  

The Global Down Syndrome Foundation is part of a network of affiliate organizations that work closely together on a daily basis to significantly improve the lives of people with Down syndrome through Research, Medical Care, Education and Advocacy.

Zack Gottsagen Hits the Big Screen Soon

Global’s Q Award Winner and his costars Shia LaBeouf and Dakota Johnson will hit movie theaters soon in their new film, The Peanut Butter Falcon. Learn about the how Zack inspired the writers to make the film and more here!

One On One With John C. McGinley

The accomplished actor tells Hallmark Channel how Global’s research & medical care changes the lives of people with Down syndrome, including his son Max.

Tune Into Our Exclusive Webinar

Find out what families need to know about the connection between lung infection and cognition from Down syndrome expert Dr. Michael Yeager.

Applications Now Open!

Global’s Employment Grants provide up to $2,000 to Down syndrome organizations to help hire and maintain employees with Down syndrome. Apply now!


People with Down syndrome have a different disease spectrum. They are highly predisposed to certain diseases like Alzheimer’s and highly protected from others, like solid tumor cancers. A donation to Global will support medical care that can increase lifespan and improve quality of life.




Become a Global Down Syndrome Foundation Member and receive 4 issues of the award-winning magazine, Down Syndrome WorldTM.