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The Latest Research & Medical Care from Our Down Syndrome Experts

New Research Discoveries and How to Participate

Tuesday, November 4, 2025
12pm – 1:15pm MT


GLOBAL Webinars are an important benefit for our Members. Held quarterly, these 1+ hour-long webinars cover topics across the lifespan. Webinars are FREE for GLOBAL Members and $10/webinar for non-Members. If you have a family member or dear friend with Down syndrome, this webinar is for you!

Join Dr. Espinosa for an exciting, unforgettable webinar that will cover his newest research discoveries and how to get involved. 

Joaquín Espinosa, PhD

Dr. Espinosa is the Executive Director of the Linda Crnic Institute for Down Syndrome and Professor of Pharmacology at the University of Colorado School of Medicine. Dr. Espinosa directs a diverse research program with emphasis on Down syndrome that is supported by the NIH INCLUDE Project and the Global Down Syndrome Foundation. At the Crnic Institute, Dr. Espinosa directs the Human Trisome Project, a detailed natural history study of the population with Down syndrome, which has enabled the design of novel clinical trials to improve health outcomes in Down syndrome.

Dr. Espinosa currently serves as the Leader of the Administrative and Outreach Core of the NIH INCLUDE Project Data Coordinating Center, a new data resource that aims to accelerate discoveries into the mechanisms underlying the increased risk of co-occurring medical conditions in people with Down syndrome.

Save The Date – Upcoming Webinars 

Tuesday, November 4, 2025 
New Research Discoveries and How to Participate 
Joaquín Espinosa, PhD

Wednesday, January 14, 2026 
Lina Patel, PsyD

Tuesday, April 7, 2026 
Brian Chicoine, MD

GLOBAL Family-Friendly Guideline

La version familiale de nos lignes directrices révolutionnaires pour les soins médicaux aux adultes atteints du syndrome de Down est disponible MAINTENANT !

GLOBAL WEBINARS – MAKING AN IMPACT

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Q&A WITH OUR EXPERTS – A VALUABLE MEMBERSHIP BENEFIT

SLEEP APNEA ACROSS THE LIFESPAN
IN PEOPLE WITH DOWN SYNDROME

Q: How does one define moderate vs severe sleep apnea? What percent in oxygen saturation during OSA episodes is the average range?

A: They are defined based on the obstructive apnea hypopnea index, which is the number of obstructive episodes during sleep divided by the hours of sleep. Many patients experience drops in oxygen saturation during obstructive episodes. These drops are variable and range from very mild to severe down to 60-70%.

DOWN SYNDROME REGRESSION DISORDER: THE LATEST RESEARCH AND PROMISING TREATMENTS

Q: What age are you seeing regression symptoms starting?

A: I think that when we’ve looked at our population level data, the mean age at onset is about 18. We see a heavy clustering in the late teen years, early twenties, and the reason why we’ve come up with this particular age range is because younger than 10, the chances that this may be autism or some other biochemical or genetic phenomenon is much higher. And similarly, over 30 is where we start to kind of bridge that gap into early onset Alzheimer’s, although that is still very young. 

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